Essential tremor surgery no thanks
Essential tremor and the surgery proposed in 2019, will be the definitive solution? The medicine itself says no, the risks are very high and the benefits are negligible.
How is the essential tremor in 2019 treated by medicine? in this post you will find all the information and already I anticipate that surgery cure the symptom , momentarily, and not the cause.I repeat that for me the cause is external and not endogenous, 3% of people affected by essential tremor are simply more sensitive to some external factors. Eliminating those external factors leads to a rapid regression of tremor.
Is it possible to eliminate the factors that cause essential tremor? Surely!!
The risks of surgery are very high, to temporarily eliminate the disturbance of essential tremor.
I say momentarily because, like all diseases, if the causes are not eliminated, the essential tremor will only be covered momentarily.
What are the treatments offered by current medicine?
Pharmacological therapies essential tremor temblor esencial
Most people with essential tremor are treated with beta-blocker, antiepileptic drugs, with the following active ingredients: propranolol, primidone, gabapentin, acetazolamide. The results are uncertain as they cause important side effects and not all treated patients have benefits.The side effects in general are:
beta-blockers (propranolol): Heart failure; Bradycardia (can occur especially in the case of use of beta-blockers without intrinsic sympathomimetic activity); Acute hypotension; Peripheral vasoconstriction; bronchoconstriction; Hypoglycemia; Gastrointestinal disorders, such as nausea, vomiting and diarrhea; dizziness; Insomnia; Depression; Nightmares and hallucinations; Vision disorders; Muscle cramps; Skin rash; Purple; Alopecia
gabapentin: severe skin reactions requiring immediate attention, swelling of the lips and face, rash and redness of the skin, and / or hair loss (these may be symptoms of a severe allergic reaction); persistent stomach pain, nausea and vomiting because these may be symptoms of acute pancreatitis (an inflammation of the pancreas); Gabapentin Pfizer can cause severe or life-threatening allergic reactions, which can affect your skin or other parts of the body such as liver or blood cells. There is the possibility or not that a rash occurs when this type of reaction occurs. This may result in your hospitalization or discontinuation of Gabapentin Pfizer treatment. Contact your doctor immediately if you have any of the following symptoms: rash, hives, fever, swelling of the glands that persists or swelling of the lips and tongue, yellowing of the skin or whites of the eyes, unusual bleeding, bruising, severe fatigue or weakness, unexpected muscle pain, frequent infections.
Very common (may affect more than 1 in 10 people): Viral infections, Feeling of drowsiness, dizziness, lack of coordination, Feeling tired, fever.
Common (may affect up to 1 in 10 people): Pneumonia, respiratory infections, urinary tract infections, ear inflammation or other infections; Low white blood cell count, Anorexia, increased appetite, anger towards other people, confusion, mood changes, depression, anxiety, nervousness, difficulty in thinking.
Convulsions, convulsive movements, difficulty in speaking, loss of memory, tremors, sleep disturbances, headaches, skin sensitivity, reduced sensitivity (numbness), difficulty in coordination, abnormalities in eye movement, increase, reduction or absence of reflexes, blurred vision, double vision, dizziness, high blood pressure, redness of the face or dilation of blood vessels, difficulty breathing, bronchitis, sore throat, cough, dry nose, Vomiting, nausea, dental problems, inflamed gums, diarrhea, stomach ache, indigestion, constipation, dry mouth or throat, flatulence, swelling of the face, bruises, rash, itching, acne, joint pain, muscle pain, back pain, muscle contractions, erection problems (impotence), swelling of the legs and arms, difficulty walking, weakness, pain, feeling sick, flu-like symptoms, white blood cell reduction, weight gain, accidental injury, fractures, abrasions In addition, aggressive behavior and convulsive movements have been commonly reported in clinical trials in children.
Uncommon (may affect up to 1 in 100 people): Allergic reaction such as hives
Reduction of movement, Increased heart rate, Swelling that can affect the face, trunk and limbs, Impaired values of blood tests that suggest problems with the liver,
Mental Impairment, Falls, Increased blood glucose levels (seen more often in patients with diabetes)
Rare (may affect up to one in 1,000 people): Loss of knowledge, Decreased blood glucose levels (seen more often in patients with diabetes)
Following the marketing phase of Gabapentin Pfizer the following undesirable effects have been reported:
Platelet reduction (cells that coagulate blood), Hallucinations, Problems with abnormal movements such as convulsive agitations, convulsive movements and stiffness, Tinkling in the ear, Some unwanted effects, including swollen lymph nodes (small nodules isolated under the skin), fever , rash, and inflammation of the liver can occur simultaneously, yellowing of the skin and eyes (jaundice). Inflammation of the liver.
Acute renal failure, incontinence, breast tissue augmentation, breast enlargement, adverse events that occur after the sudden suspension of gabapentin (anxiety, sleep disturbance, feeling sick, pain, sweating), chest pain.
Injury of muscle fibers (rhabdomyolysis). Abnormalities in blood tests (increase in creatine phosphokinase). Problems of sexual function including the inability to achieve orgasm, delayed ejaculation.
Acetazolamide may induce: nausea, vomiting, diarrhea, taste changes, loss of appetite, paresthesia, skin rash, headache, dizziness, tiredness, irritability, depression, thirst, polyuria; decrease in libido; metabolic acidosis and electrolyte disturbances for long-term therapies; sometimes drowsiness, mental confusion, hearing disorders, hives, melena, glycosuria, haematuria, abnormal liver function, kidney stone formation, haematological abnormalities including agranulocytosis, and thrombocytopenia, rash including Stevens-Johnson syndrome and epidermal toxic necrolysis; rarely photosensitivity, hepatic damage, flaccid paralysis, convulsions; cases of transient myopia have been reported. Acetazolamide may induce nausea, vomiting, diarrhea, changes in taste, loss of appetite, paresthesia, skin rash, headache, dizziness, tiredness, irritability, depression, thirst, polyuria; decrease in libido; metabolic acidosis and electrolyte disturbances for long-term therapies; sometimes drowsiness, mental confusion, hearing disorders, hives, melena, glycosuria, haematuria, abnormal liver function, kidney stone formation, haematological abnormalities including agranulocytosis, and thrombocytopenia, rash including Stevens-Johnson syndrome and epidermal toxic necrolysis; rarely photosensitivity, hepatic damage, flaccid paralysis, convulsions; cases of transient myopia have been reported.
Talamotomy for essential tremor
Neurosurgical intervention consisting in the practice of a lesion (controlled destruction of brain tissue) in the area of the brain at the origin of tremors. Thalamotomy has proven effective in reducing tremor in some subjects.The side effects in general are:
Potential complications include problems with language, balance, cerebral bleeding and numbness.
Deep brain stimulation (DBS) for the treatment of essential tremor
DBS therapy for essential tremor is a surgical treatment able to reduce the intensity of the arm and hand tremor associated with the disease.The treatment uses a surgically implanted medical device, similar to a pacemaker, to send electrical stimulation to certain areas of the brain. Stimulation blocks the messages of the brain that cause the symptoms of essential tremor.
The side effects in general are:
The side effects of this treatment are infections, problems with language, balance, cerebral bleeding and numbness.
MRg-FUS
MRg-FUS is a minimally invasive procedure, however of a lesional nature, so it is not without risks. The main risks are caused by cerebral edema, which may develop in the period following the MRgFUS procedure.The side effects in general are:
The patient may experience side effects such as speech disturbances, an uncertain gait or numbness, involuntary movements or weakness in the treated arm or leg.
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